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| Date |
Type |
Title |
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Jul 19, 2008 |
Abstract |
Cardiorespiratory fitness and brain atrophy in early Alzheimer disease - Source: Neurology, July 2008
Increased cardiorespiratory fitness is linked to less brain atrophy in early Alzheimer disease and may moderate a common underlying process that affects both brain atrophy and fitness. [Source: Neurology, July 2008] |
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Jul 10, 2008 |
Article |
Ionophore compound (PBT2) reverses Alzheimer’s within days in mouse models - first human trials also promising
Australian brain research collaborative reports that an ionophore compound (PBT2), fed to mice in special tomatoes, reversed Alzheimer's by detoxifying beta-amyloid plaques of zinc and copper, causing the plaques to disperse very rapidly. And recent clinical trials in human AD patients have been promising. |
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Jul 01, 2008 |
Article,ClinicalTrial,DrugNews,Events |
UCLA – Trial of drug to improve cognition & function in adults with depression, ages 60 and older (not yet recruiting)
This 16-week NIH-sponsored study in Los Angeles – Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults with Depression - will recruit patients age 60 and older. |
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Jul 01, 2008 |
Article,ClinicalTrial,Events |
NIH Depression Drug Trials Now Recruiting in 13 States
Male and female patients ages 18 to 75 with chronic and/or recurrent major depression are now being recruited for a trial titled Combining Medications to Enhance Depression Outcomes (CO-MED) - sponsored by the National Institute of Mental Health (NIMH). |
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Jun 30, 2008 |
Abstract |
Prevalence and Correlates of Silent Cerebral Infarcts in the Framingham Offspring Study – Source: Stroke, June 26, 2008
MRIs show 1 in 10 apparently healthy people at mid-life has injury from silent strokes. These go unnoted, but are associated with uncontrolled high blood pressure and artery disease, and are risk factors for dementia, clinical strokes, and atrial fibrillation. [Source: Stroke, June 26, 2008] |
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Jun 29, 2008 |
Article |
Adults with type 2 diabetes may experience memory declines immediately after eating unhealthy meal
Amazingly, the acute negative effect on memory of high-fat meals can be offset by taking antioxidant vitamins with the meal - though a healthy diet rich in fruits and vegetables should be first defense. |
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Jun 29, 2008 |
Abstract |
Antioxidant vitamins reduce acute meal-induced memory deficits in adults with type 2 diabetes - Source: Nutrition Research, July 2008
Amazingly, the memory problems that swiftly followed high-fat meals in this study were avoided when subjects took antioxidant vitamins with the meal - presumably because the problems were caused by free radicals. A healthy diet rich in fruits and vegetables is the preferred preventive. [Source: Nutrition Research, July 2008] |
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Jun 02, 2008 |
Abstract |
Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: A randomized phase II trial - Source: The Lancet Neurology, June 2008
In 2-year UK/Canada trial, anti-amyloid (plaque) drug clearly slowed rate of decline in daily function, concentration, memory vs. placebo patients – but only for those diagnosed early with very mild form of illness. Larger phase III trial results may soon clarify potential. Source: The Lancet Neurology, June 2008 |
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May 29, 2008 |
Article |
National Institute on Aging Seeking Participants for Alzheimer’s Disease Genetics Studies
The NIA’s National Cell Repository for Alzheimer’s Disease (NCRAD) is seeking families to contribute blood samples for ongoing genetic studies. |
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Apr 09, 2008 |
Abstract |
B-vitamins reduce plasma levels of beta amyloid – Source: Neurobiology of Aging, Feb 2008
Placebo-controlled trial reports 75% reduced increase of plaque-component AB40 in blood of older men receiving B vitamins - which “may have a role in the prevention of Alzheimer’s disease.” [Source: Neurobiology of Aging, Feb 2008] |
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